Clozapine

Brand name: Clozaril

Description

Antipsychotic
The drug has been found to be effective in the treatment of patients with bipolar and manic-depressive disorder
Brands: Versacloz, FazaClo, And Clozaril
Availability: Prescription needed
Pregnancy: No known risks
Alcohol: It is dangerous to use it together
Side Effects: Difficulty In Passing Urine (dribbling), Trembling Or Shaking Of The Hands Or Feet, Black, Tarry Stools
Interactions: Geodon (ziprasidone), Lamictal (lamotrigine), Zyprexa (olanzapine)
For informational purposes only. Consult your local medical authority for advice.

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The medication was initially developed by Neurimmune and has been licensed to Alexion, the rare disease unit of AstraZeneca.

What may interact with Clozaril?

Do not take Clozaril with any of the following medications:

  • cisapride
  • medicines for treating cancer
  • mibefradil
  • olanzapine
  • phenothiazines like perphenazine, thioridazine and chlorpromazine
  • pimozide
  • ziprasidone

Clozaril may also interact with the following medications:

  • caffeine
  • carbamazepine
  • cimetidine
  • ciprofloxacin
  • erythromycin or clarithromycin
  • lithium
  • medicines for anxiety or sleeping problems, such as diazepam or temazepam
  • medicines for colds, hay fever, and other allergies
  • medicines for high blood pressure
  • medicines for mental depression, anxiety, or other mood problems
  • nicotine
  • phenytoin
  • rifampin or rifabutin
  • some medicines used to treat irregular heartbeats

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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